Six men and two women died in the collision, while a woman, a man and a five-year-old girl who were also in the minibus were taken to hospital with life-threatening injuries.
Ryszard Masierak, 31, and David Wagstaff, 53, were both charged with eight counts of causing death by dangerous driving and four counts of causing serious injury by dangerous driving.
The former was also charged with eight counts of causing death by careless driving while over the prescribed limit.
Masierak, of Barnards Close, Evesham, Worcestershire, was remanded in custody and will appear at High Wycombe Magistrates' Court on Monday.
Meanwhile, Wagstaff, of Derwent Street, Stoke-on-Trent, was bailed to appear at Milton Keynes Magistrates' Court on 11 September.
