It is all part of the smart motorway works taking place on the M1 near Milton Keynes.
A spokesperson for National Highways said: "Roadworks affect all journeys which is why it is important they are completed as quickly and safely as possible. Our overnight closures are under constant review and we aim to open the road earlier than the times displayed wherever possible.
"Please be considerate of residents living along the diversion routes when travelling during these closures. Closures can only be installed once traffic flows are at their lowest."
Drivers are being warned to plan ahead when travelling, as it may disrupt late or early journeys.
Southbound
On Tuesday 3rd May, the full carriageway is set to be shut between Junction 15 - Junction 13. This closure will remain in place for two nights between 9pm and 5am.
From Friday 6 May for 3 nights, a full closure will be in place between Junction 15a - Junction 15, near Milton Keynes, between 9pm and 6am.
Tuesday 10 May for 3 nights, 9pm - 6am, Junction 16 - Junction 15 full carriageway closure
Friday 13 May, 9pm- 6am, Junction 15a - Junction 15 full carriageway closure, Junction 16 - 15a, Lanes 3 and 2 closed, Junction 15 - 14, Lanes 1 and 2 closed, Junction 15a entry slip closed.
Northbound
Friday 6 May for 3 nights, Junction 13 - Junction 14 full carriageway full closure between 10pm and 6am.
You can find out more and keep up to date here.
